PoplarV1, Main, Exploration, bibRecord, 000F51

Downregulating aspen xylan biosynthetic GT43 genes in developing wood stimulates growth via reprograming of the transcriptome.

Identifieur interne : 000F51 ( Main/Exploration ); précédent : 000F50; suivant : 000F52

Downregulating aspen xylan biosynthetic GT43 genes in developing wood stimulates growth via reprograming of the transcriptome.

Auteurs : Christine Ratke [Suède] ; Barbara K. Terebieniec [Suède] ; Sandra Winestrand [Suède] ; Marta Derba-Maceluch [Suède] ; Thomas Grahn [Suède] ; Bastian Schiffthaler [Suède] ; Thomas Ulvcrona [Suède] ; Merve Özparpucu [Suisse] ; Markus Rüggeberg [Suisse] ; Sven-Olof Lundqvist [Suède] ; Nathaniel R. Street [Suède] ; Leif J. Jönsson [Suède] ; Ewa J. Mellerowicz [Suède]

Source :

The New phytologist [ 1469-8137 ] ; 2018.

RBID : pubmed:29708593

Descripteurs français

KwdFr :
- Bois (composition chimique), Bois (croissance et développement), Bois (génétique), Cambium (croissance et développement), Cambium (génétique), Cellulose (génétique), Cellulose (métabolisme), Chimère (MeSH), Famille multigénique (MeSH), Interférence par ARN (MeSH), Lignine (génétique), Lignine (métabolisme), Paroi cellulaire (composition chimique), Paroi cellulaire (génétique), Populus (croissance et développement), Populus (génétique), Protéines végétales (génétique), Protéines végétales (métabolisme), Régions promotrices (génétique) (MeSH), Régulation de l'expression des gènes végétaux (MeSH), Régulation négative (MeSH), Sucres (métabolisme), Végétaux génétiquement modifiés (MeSH), Xylanes (biosynthèse), Xylanes (génétique).
MESH :
- biosynthèse : Xylanes.
- composition chimique : Bois, Paroi cellulaire.
- croissance et développement : Bois, Cambium, Populus.
- génétique : Bois, Cambium, Cellulose, Lignine, Paroi cellulaire, Populus, Protéines végétales, Xylanes.
- métabolisme : Cellulose, Lignine, Protéines végétales, Sucres.
- Chimère, Famille multigénique, Interférence par ARN, Régions promotrices (génétique), Régulation de l'expression des gènes végétaux, Régulation négative, Végétaux génétiquement modifiés.

English descriptors

KwdEn :
- Cambium (genetics), Cambium (growth & development), Cell Wall (chemistry), Cell Wall (genetics), Cellulose (genetics), Cellulose (metabolism), Chimera (MeSH), Down-Regulation (MeSH), Gene Expression Regulation, Plant (MeSH), Lignin (genetics), Lignin (metabolism), Multigene Family (MeSH), Plant Proteins (genetics), Plant Proteins (metabolism), Plants, Genetically Modified (MeSH), Populus (genetics), Populus (growth & development), Promoter Regions, Genetic (MeSH), RNA Interference (MeSH), Sugars (metabolism), Wood (chemistry), Wood (genetics), Wood (growth & development), Xylans (biosynthesis), Xylans (genetics).
MESH :
- chemical , biosynthesis : Xylans.
- chemical , genetics : Cellulose, Lignin, Plant Proteins, Xylans.
- chemistry : Cell Wall, Wood.
- genetics : Cambium, Cell Wall, Populus, Wood.
- growth & development : Cambium, Populus, Wood.
- chemical , metabolism : Cellulose, Lignin, Plant Proteins, Sugars.
- Chimera, Down-Regulation, Gene Expression Regulation, Plant, Multigene Family, Plants, Genetically Modified, Promoter Regions, Genetic, RNA Interference.

Abstract

Xylan is one of the main compounds determining wood properties in hardwood species. The xylan backbone is thought to be synthesized by a synthase complex comprising two members of the GT43 family. We downregulated all GT43 genes in hybrid aspen (Populus tremula × tremuloides) to understand their involvement in xylan biosynthesis. All three clades of the GT43 family were targeted for downregulation using RNA interference individually or in different combinations, either constitutively or specifically in developing wood. Simultaneous downregulation in developing wood of the B (IRX9) and C (IRX14) clades resulted in reduced xylan Xyl content relative to reducing end sequence, supporting their role in xylan backbone biosynthesis. This was accompanied by a higher lignocellulose saccharification efficiency. Unexpectedly, GT43 suppression in developing wood led to an overall growth stimulation, xylem cell wall thinning and a shift in cellulose orientation. Transcriptome profiling of these transgenic lines indicated that cell cycling was stimulated and secondary wall biosynthesis was repressed. We suggest that the reduced xylan elongation is sensed by the cell wall integrity surveying mechanism in developing wood. Our results show that wood-specific suppression of xylan-biosynthetic GT43 genes activates signaling responses, leading to increased growth and improved lignocellulose saccharification.

DOI: 10.1111/nph.15160
PubMed: 29708593

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<author><name sortKey="Ozparpucu, Merve" sort="Ozparpucu, Merve" uniqKey="Ozparpucu M" first="Merve" last="Özparpucu">Merve Özparpucu</name>
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<author><name sortKey="Jonsson, Leif J" sort="Jonsson, Leif J" uniqKey="Jonsson L" first="Leif J" last="Jönsson">Leif J. Jönsson</name>
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<wicri:noRegion>Umeå</wicri:noRegion>
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<author><name sortKey="Mellerowicz, Ewa J" sort="Mellerowicz, Ewa J" uniqKey="Mellerowicz E" first="Ewa J" last="Mellerowicz">Ewa J. Mellerowicz</name>
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<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå</wicri:regionArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Downregulating aspen xylan biosynthetic GT43 genes in developing wood stimulates growth via reprograming of the transcriptome.</title>
<author><name sortKey="Ratke, Christine" sort="Ratke, Christine" uniqKey="Ratke C" first="Christine" last="Ratke">Christine Ratke</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
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<author><name sortKey="Terebieniec, Barbara K" sort="Terebieniec, Barbara K" uniqKey="Terebieniec B" first="Barbara K" last="Terebieniec">Barbara K. Terebieniec</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
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<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
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<author><name sortKey="Winestrand, Sandra" sort="Winestrand, Sandra" uniqKey="Winestrand S" first="Sandra" last="Winestrand">Sandra Winestrand</name>
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<author><name sortKey="Derba Maceluch, Marta" sort="Derba Maceluch, Marta" uniqKey="Derba Maceluch M" first="Marta" last="Derba-Maceluch">Marta Derba-Maceluch</name>
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<country xml:lang="fr">Suède</country>
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<author><name sortKey="Grahn, Thomas" sort="Grahn, Thomas" uniqKey="Grahn T" first="Thomas" last="Grahn">Thomas Grahn</name>
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<author><name sortKey="Schiffthaler, Bastian" sort="Schiffthaler, Bastian" uniqKey="Schiffthaler B" first="Bastian" last="Schiffthaler">Bastian Schiffthaler</name>
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<country xml:lang="fr">Suède</country>
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<author><name sortKey="Ulvcrona, Thomas" sort="Ulvcrona, Thomas" uniqKey="Ulvcrona T" first="Thomas" last="Ulvcrona">Thomas Ulvcrona</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Forest Resource Management, SLU, S-901-83, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Forest Resource Management, SLU, S-901-83, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
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<author><name sortKey="Ozparpucu, Merve" sort="Ozparpucu, Merve" uniqKey="Ozparpucu M" first="Merve" last="Özparpucu">Merve Özparpucu</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute for Building Materials, Swiss Federal Institute of Technology (ETH Zürich), CH-8093, Zürich, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute for Building Materials, Swiss Federal Institute of Technology (ETH Zürich), CH-8093, Zürich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
</affiliation>
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<author><name sortKey="Ruggeberg, Markus" sort="Ruggeberg, Markus" uniqKey="Ruggeberg M" first="Markus" last="Rüggeberg">Markus Rüggeberg</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute for Building Materials, Swiss Federal Institute of Technology (ETH Zürich), CH-8093, Zürich, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Institute for Building Materials, Swiss Federal Institute of Technology (ETH Zürich), CH-8093, Zürich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lundqvist, Sven Olof" sort="Lundqvist, Sven Olof" uniqKey="Lundqvist S" first="Sven-Olof" last="Lundqvist">Sven-Olof Lundqvist</name>
<affiliation wicri:level="3"><nlm:affiliation>Material Processes, RISE Innventia AB, SE-114-86, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Material Processes, RISE Innventia AB, SE-114-86, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Street, Nathaniel R" sort="Street, Nathaniel R" uniqKey="Street N" first="Nathaniel R" last="Street">Nathaniel R. Street</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Physiology, Umeå University, S-901-87, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Plant Physiology, Umeå University, S-901-87, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jonsson, Leif J" sort="Jonsson, Leif J" uniqKey="Jonsson L" first="Leif J" last="Jönsson">Leif J. Jönsson</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Umeå University, S-901-87, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Chemistry, Umeå University, S-901-87, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mellerowicz, Ewa J" sort="Mellerowicz, Ewa J" uniqKey="Mellerowicz E" first="Ewa J" last="Mellerowicz">Ewa J. Mellerowicz</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå</wicri:regionArea>
<wicri:noRegion>Umeå</wicri:noRegion>
</affiliation>
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<series><title level="j">The New phytologist</title>
<idno type="eISSN">1469-8137</idno>
<imprint><date when="2018" type="published">2018</date>
</imprint>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cambium (genetics)</term>
<term>Cambium (growth & development)</term>
<term>Cell Wall (chemistry)</term>
<term>Cell Wall (genetics)</term>
<term>Cellulose (genetics)</term>
<term>Cellulose (metabolism)</term>
<term>Chimera (MeSH)</term>
<term>Down-Regulation (MeSH)</term>
<term>Gene Expression Regulation, Plant (MeSH)</term>
<term>Lignin (genetics)</term>
<term>Lignin (metabolism)</term>
<term>Multigene Family (MeSH)</term>
<term>Plant Proteins (genetics)</term>
<term>Plant Proteins (metabolism)</term>
<term>Plants, Genetically Modified (MeSH)</term>
<term>Populus (genetics)</term>
<term>Populus (growth & development)</term>
<term>Promoter Regions, Genetic (MeSH)</term>
<term>RNA Interference (MeSH)</term>
<term>Sugars (metabolism)</term>
<term>Wood (chemistry)</term>
<term>Wood (genetics)</term>
<term>Wood (growth & development)</term>
<term>Xylans (biosynthesis)</term>
<term>Xylans (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Bois (composition chimique)</term>
<term>Bois (croissance et développement)</term>
<term>Bois (génétique)</term>
<term>Cambium (croissance et développement)</term>
<term>Cambium (génétique)</term>
<term>Cellulose (génétique)</term>
<term>Cellulose (métabolisme)</term>
<term>Chimère (MeSH)</term>
<term>Famille multigénique (MeSH)</term>
<term>Interférence par ARN (MeSH)</term>
<term>Lignine (génétique)</term>
<term>Lignine (métabolisme)</term>
<term>Paroi cellulaire (composition chimique)</term>
<term>Paroi cellulaire (génétique)</term>
<term>Populus (croissance et développement)</term>
<term>Populus (génétique)</term>
<term>Protéines végétales (génétique)</term>
<term>Protéines végétales (métabolisme)</term>
<term>Régions promotrices (génétique) (MeSH)</term>
<term>Régulation de l'expression des gènes végétaux (MeSH)</term>
<term>Régulation négative (MeSH)</term>
<term>Sucres (métabolisme)</term>
<term>Végétaux génétiquement modifiés (MeSH)</term>
<term>Xylanes (biosynthèse)</term>
<term>Xylanes (génétique)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Xylans</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cellulose</term>
<term>Lignin</term>
<term>Plant Proteins</term>
<term>Xylans</term>
</keywords>
<keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Xylanes</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Cell Wall</term>
<term>Wood</term>
</keywords>
<keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Bois</term>
<term>Paroi cellulaire</term>
</keywords>
<keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Bois</term>
<term>Cambium</term>
<term>Populus</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Cambium</term>
<term>Cell Wall</term>
<term>Populus</term>
<term>Wood</term>
</keywords>
<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Cambium</term>
<term>Populus</term>
<term>Wood</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Bois</term>
<term>Cambium</term>
<term>Cellulose</term>
<term>Lignine</term>
<term>Paroi cellulaire</term>
<term>Populus</term>
<term>Protéines végétales</term>
<term>Xylanes</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Cellulose</term>
<term>Lignin</term>
<term>Plant Proteins</term>
<term>Sugars</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cellulose</term>
<term>Lignine</term>
<term>Protéines végétales</term>
<term>Sucres</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Chimera</term>
<term>Down-Regulation</term>
<term>Gene Expression Regulation, Plant</term>
<term>Multigene Family</term>
<term>Plants, Genetically Modified</term>
<term>Promoter Regions, Genetic</term>
<term>RNA Interference</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Chimère</term>
<term>Famille multigénique</term>
<term>Interférence par ARN</term>
<term>Régions promotrices (génétique)</term>
<term>Régulation de l'expression des gènes végétaux</term>
<term>Régulation négative</term>
<term>Végétaux génétiquement modifiés</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Xylan is one of the main compounds determining wood properties in hardwood species. The xylan backbone is thought to be synthesized by a synthase complex comprising two members of the GT43 family. We downregulated all GT43 genes in hybrid aspen (Populus tremula × tremuloides) to understand their involvement in xylan biosynthesis. All three clades of the GT43 family were targeted for downregulation using RNA interference individually or in different combinations, either constitutively or specifically in developing wood. Simultaneous downregulation in developing wood of the B (IRX9) and C (IRX14) clades resulted in reduced xylan Xyl content relative to reducing end sequence, supporting their role in xylan backbone biosynthesis. This was accompanied by a higher lignocellulose saccharification efficiency. Unexpectedly, GT43 suppression in developing wood led to an overall growth stimulation, xylem cell wall thinning and a shift in cellulose orientation. Transcriptome profiling of these transgenic lines indicated that cell cycling was stimulated and secondary wall biosynthesis was repressed. We suggest that the reduced xylan elongation is sensed by the cell wall integrity surveying mechanism in developing wood. Our results show that wood-specific suppression of xylan-biosynthetic GT43 genes activates signaling responses, leading to increased growth and improved lignocellulose saccharification.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29708593</PMID>
<DateCompleted><Year>2019</Year>
<Month>09</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>09</Month>
<Day>30</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1469-8137</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>219</Volume>
<Issue>1</Issue>
<PubDate><Year>2018</Year>
<Month>07</Month>
</PubDate>
</JournalIssue>
<Title>The New phytologist</Title>
<ISOAbbreviation>New Phytol</ISOAbbreviation>
</Journal>
<ArticleTitle>Downregulating aspen xylan biosynthetic GT43 genes in developing wood stimulates growth via reprograming of the transcriptome.</ArticleTitle>
<Pagination><MedlinePgn>230-245</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/nph.15160</ELocationID>
<Abstract><AbstractText>Xylan is one of the main compounds determining wood properties in hardwood species. The xylan backbone is thought to be synthesized by a synthase complex comprising two members of the GT43 family. We downregulated all GT43 genes in hybrid aspen (Populus tremula × tremuloides) to understand their involvement in xylan biosynthesis. All three clades of the GT43 family were targeted for downregulation using RNA interference individually or in different combinations, either constitutively or specifically in developing wood. Simultaneous downregulation in developing wood of the B (IRX9) and C (IRX14) clades resulted in reduced xylan Xyl content relative to reducing end sequence, supporting their role in xylan backbone biosynthesis. This was accompanied by a higher lignocellulose saccharification efficiency. Unexpectedly, GT43 suppression in developing wood led to an overall growth stimulation, xylem cell wall thinning and a shift in cellulose orientation. Transcriptome profiling of these transgenic lines indicated that cell cycling was stimulated and secondary wall biosynthesis was repressed. We suggest that the reduced xylan elongation is sensed by the cell wall integrity surveying mechanism in developing wood. Our results show that wood-specific suppression of xylan-biosynthetic GT43 genes activates signaling responses, leading to increased growth and improved lignocellulose saccharification.</AbstractText>
<CopyrightInformation>© 2018 The Authors. New Phytologist © 2018 New Phytologist Trust.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ratke</LastName>
<ForeName>Christine</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Terebieniec</LastName>
<ForeName>Barbara K</ForeName>
<Initials>BK</Initials>
<AffiliationInfo><Affiliation>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Winestrand</LastName>
<ForeName>Sandra</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Chemistry, Umeå University, S-901-87, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Derba-Maceluch</LastName>
<ForeName>Marta</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Grahn</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Material Processes, RISE Innventia AB, SE-114-86, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schiffthaler</LastName>
<ForeName>Bastian</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Plant Physiology, Umeå University, S-901-87, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ulvcrona</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Forest Resource Management, SLU, S-901-83, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Özparpucu</LastName>
<ForeName>Merve</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute for Building Materials, Swiss Federal Institute of Technology (ETH Zürich), CH-8093, Zürich, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rüggeberg</LastName>
<ForeName>Markus</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute for Building Materials, Swiss Federal Institute of Technology (ETH Zürich), CH-8093, Zürich, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lundqvist</LastName>
<ForeName>Sven-Olof</ForeName>
<Initials>SO</Initials>
<AffiliationInfo><Affiliation>Material Processes, RISE Innventia AB, SE-114-86, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Street</LastName>
<ForeName>Nathaniel R</ForeName>
<Initials>NR</Initials>
<AffiliationInfo><Affiliation>Department of Plant Physiology, Umeå University, S-901-87, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jönsson</LastName>
<ForeName>Leif J</ForeName>
<Initials>LJ</Initials>
<AffiliationInfo><Affiliation>Department of Chemistry, Umeå University, S-901-87, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mellerowicz</LastName>
<ForeName>Ewa J</ForeName>
<Initials>EJ</Initials>
<Identifier Source="ORCID">0000-0001-6817-1031</Identifier>
<AffiliationInfo><Affiliation>Department of Forest Genetics and Plant Physiology, SLU, Umeå Plant Science Centre (UPSC), S-901-83, Umeå, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>04</Month>
<Day>30</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>New Phytol</MedlineTA>
<NlmUniqueID>9882884</NlmUniqueID>
<ISSNLinking>0028-646X</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D010940">Plant Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000073893">Sugars</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014990">Xylans</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>9004-34-6</RegistryNumber>
<NameOfSubstance UI="D002482">Cellulose</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>9005-53-2</RegistryNumber>
<NameOfSubstance UI="D008031">Lignin</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D058506" MajorTopicYN="N">Cambium</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002473" MajorTopicYN="N">Cell Wall</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002482" MajorTopicYN="N">Cellulose</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002678" MajorTopicYN="N">Chimera</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015536" MajorTopicYN="N">Down-Regulation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018506" MajorTopicYN="N">Gene Expression Regulation, Plant</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008031" MajorTopicYN="N">Lignin</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005810" MajorTopicYN="N">Multigene Family</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010940" MajorTopicYN="N">Plant Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D030821" MajorTopicYN="N">Plants, Genetically Modified</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D032107" MajorTopicYN="N">Populus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011401" MajorTopicYN="N">Promoter Regions, Genetic</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D034622" MajorTopicYN="N">RNA Interference</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073893" MajorTopicYN="N">Sugars</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014934" MajorTopicYN="N">Wood</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000254" MajorTopicYN="Y">growth & development</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014990" MajorTopicYN="N">Xylans</DescriptorName>
<QualifierName UI="Q000096" MajorTopicYN="Y">biosynthesis</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Populus
</Keyword>
<Keyword MajorTopicYN="Y">GT43</Keyword>
<Keyword MajorTopicYN="Y">cellulose microfibril angle</Keyword>
<Keyword MajorTopicYN="Y">saccharification</Keyword>
<Keyword MajorTopicYN="Y">secondary wall</Keyword>
<Keyword MajorTopicYN="Y">wood development</Keyword>
<Keyword MajorTopicYN="Y">xylan biosynthesis</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year>
<Month>12</Month>
<Day>18</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>03</Month>
<Day>02</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2018</Year>
<Month>5</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>10</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2018</Year>
<Month>5</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">29708593</ArticleId>
<ArticleId IdType="doi">10.1111/nph.15160</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Suisse</li>
<li>Suède</li>
</country>
<region><li>Canton de Zurich</li>
<li>Svealand</li>
</region>
<settlement><li>Stockholm</li>
<li>Zurich</li>
</settlement>
</list>
<tree><country name="Suède"><noRegion><name sortKey="Ratke, Christine" sort="Ratke, Christine" uniqKey="Ratke C" first="Christine" last="Ratke">Christine Ratke</name>
</noRegion>
<name sortKey="Derba Maceluch, Marta" sort="Derba Maceluch, Marta" uniqKey="Derba Maceluch M" first="Marta" last="Derba-Maceluch">Marta Derba-Maceluch</name>
<name sortKey="Grahn, Thomas" sort="Grahn, Thomas" uniqKey="Grahn T" first="Thomas" last="Grahn">Thomas Grahn</name>
<name sortKey="Jonsson, Leif J" sort="Jonsson, Leif J" uniqKey="Jonsson L" first="Leif J" last="Jönsson">Leif J. Jönsson</name>
<name sortKey="Lundqvist, Sven Olof" sort="Lundqvist, Sven Olof" uniqKey="Lundqvist S" first="Sven-Olof" last="Lundqvist">Sven-Olof Lundqvist</name>
<name sortKey="Mellerowicz, Ewa J" sort="Mellerowicz, Ewa J" uniqKey="Mellerowicz E" first="Ewa J" last="Mellerowicz">Ewa J. Mellerowicz</name>
<name sortKey="Schiffthaler, Bastian" sort="Schiffthaler, Bastian" uniqKey="Schiffthaler B" first="Bastian" last="Schiffthaler">Bastian Schiffthaler</name>
<name sortKey="Street, Nathaniel R" sort="Street, Nathaniel R" uniqKey="Street N" first="Nathaniel R" last="Street">Nathaniel R. Street</name>
<name sortKey="Terebieniec, Barbara K" sort="Terebieniec, Barbara K" uniqKey="Terebieniec B" first="Barbara K" last="Terebieniec">Barbara K. Terebieniec</name>
<name sortKey="Ulvcrona, Thomas" sort="Ulvcrona, Thomas" uniqKey="Ulvcrona T" first="Thomas" last="Ulvcrona">Thomas Ulvcrona</name>
<name sortKey="Winestrand, Sandra" sort="Winestrand, Sandra" uniqKey="Winestrand S" first="Sandra" last="Winestrand">Sandra Winestrand</name>
</country>
<country name="Suisse"><region name="Canton de Zurich"><name sortKey="Ozparpucu, Merve" sort="Ozparpucu, Merve" uniqKey="Ozparpucu M" first="Merve" last="Özparpucu">Merve Özparpucu</name>
</region>
<name sortKey="Ruggeberg, Markus" sort="Ruggeberg, Markus" uniqKey="Ruggeberg M" first="Markus" last="Rüggeberg">Markus Rüggeberg</name>
</country>
</tree>
</affiliations>
</record>

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Downregulating aspen xylan biosynthetic GT43 genes in developing wood stimulates growth via reprograming of the transcriptome.

Downregulating aspen xylan biosynthetic GT43 genes in developing wood stimulates growth via reprograming of the transcriptome.

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